Hemostasis Test 2

How does GPIb become activated in vivo and in vitro, respectively?

A patient is on aspirin 100 mg/day to prevent the formation of clots caused by platelets. The mechanism in which aspirin impairs platelet function is by:

A patient is diagnosed with a factor V Leiden mutation. The factor V activity level should be:

The International Sensitivity Index (ISI) is determined by comparing the PT results of the manufacturer’s reagent against:

A coagulation reagent should be sensitive to factor deficiencies. A reagent is considered sensitive to a factor when the level of factor activity is approximately:

What factors are considered heat labile?

What factor serves as a carrier for factor VIII?

Patients may present with either a bleeding or a thrombotic event in:

The key enzyme of the fibrinolytic system is:

The major serine protease responsible for clot breakdown is:

What subendothelial structural protein triggers coagulation through activation of FVII?

Protein C and its cofactor protein S proteolytically inactivate factors:

Arterial thrombosis is caused by:

The 2 factors that differentiate liver disease from vitamin K deficiency are:

In a patient diagnosed with liver disease, which one of the following factors typically shows an increase?

A 4-year-old boy presents with chronic ear infections and is on prophylactic antibiotics. He also presents with a bleeding diathesis. Factor assay results are shown in this table:

Possible causes are:

A hemophiliac male and a normal female can produce a:

Hemophilia B is a sex-linked recessive disorder that presents with a decrease in factor:

To distinguish between hemophilia and von Willebrand disease, a patient with von Willebrand will present with which of the following test results?

A patient presents with bleeding 48 hours after tooth extraction. Results are shown in this table:

The cause of bleeding is most likely a deficiency in: